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Liposomal Vitamin C

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About Us
China Joyful Nutritional Supply Co.,ltd
Joyful Nutritional Supply Co.,ltd
Joyful Nutritional is a ISO22000 verified leading manufacturer and solution provider of mineral ingredients including calcium, iron, zinc, selenium, and magnesium etc. Our production facility covers an area of 10,000 square meters and has several intelligent production lines and one testing laboratory approved by CNAS. We developed production and application technologies such as Microencapsulation, Activation, Embedding and lipidization, which solve and meet the unique needs of customers.
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01
FSSC22000 Food Safety Certified
The quality management system of Joyful Nutritional's production facility had been FSSC 22000 Verified
02
100000 ㎡ Production Area with 4 Production Lines
Our production facility covers an area of We have 4 Intelligent 100000 ㎡ with four intelligent production lines
03
CNAS Certified Laboratory
Joyful Nutritional is equipped with advanced laboratory certified by CNAS to ensure the products undergoes Rigorous Testing
04
Innovation in Solutions and Technology
Customized solutions including Microencapsulation,Dilution and Granulation,Emulsification,Microcrystals and embedding
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Latest company news about LiposoMore™ Redefines Bioavailability: Joyful Nutritional Launches High-Performance Liposomal Vitamin C and Iron for the Global Supplement Market
2026-04-22

LiposoMore™ Redefines Bioavailability: Joyful Nutritional Launches High-Performance Liposomal Vitamin C and Iron for the Global Supplement Market

Shenzhen,Guangdong Province, China — Joyful Nutritional, a leading innovator in advanced nutrient delivery systems, is proud to announce the official global launch of LiposoMore™, its premier brand of high-performance liposomal ingredients.   Targeting the burgeoning B2B dietary supplement sector, LiposoMore™ debuts with two flagship products: Liposomal Vitamin C Powder and Liposomal Iron (Ferric Pyrophosphate) Powder.   As the global supplement industry shifts toward "clean label" efficacy and scientifically proven absorption, LiposoMore™ provides manufacturers, brand owners, and Contract Manufacturing Organizations (CMOs) with a sophisticated solution to the perennial challenges of nutrient stability and bioavailability.       Engineering the Future of Nutrient Delivery The core of the LiposoMore™ brand lies in its proprietary liposomal encapsulation technology. By utilizing a phospholipid bilayer structure that mimics human cell membranes, LiposoMore™ protects active ingredients from the harsh acidic environment of the gastrointestinal tract. This ensures that the nutrients reach the small intestine intact, where they are absorbed more efficiently into the bloodstream.   “The launch of LiposoMore™ marks a pivotal moment for Joyful Nutritional,” said a spokesperson for the brand. “Our mission is to bridge the gap between high-dose supplementation and actual physiological uptake. For R&D professionals, LiposoMore™ isn't just a raw material; it’s a tool to create products that consumers can actually feel working.”     Liposomal Vitamin C: Stability Meets High Absorption Traditional Vitamin C (Ascorbic Acid) is notorious for its poor stability and potential for gastric irritation at high doses. LiposoMore™ Vitamin C Powder addresses these hurdles through a refined encapsulation process.   ● Enhanced Stability: The liposomal matrix acts as a shield against light and oxygen, extending shelf life in final formulations.   ● Gastric Comfort: By encapsulating the acidic Vitamin C within lipids, LiposoMore™ significantly reduces stomach upset, allowing for higher, more effective dosages.   ● Versatility: Engineered for excellent flowability, the powder is optimized for capsules, tablets, and dry-mix sachets.     Liposomal Iron: A Breakthrough in Sensory and Gastric Tolerance Iron deficiency remains one of the most common nutritional gaps worldwide, yet traditional iron salts often suffer from poor compliance due to a metallic aftertaste and digestive side effects. LiposoMore™ Liposomal Iron utilizes Ferric Pyrophosphate , a non-heme iron source, re-engineered for the modern consumer.   ● Taste Masking: The liposomal layer effectively masks the metallic taste of iron, making it ideal for chewables, gummies, and liquid-suspension powders.   ● Superior Bioavailability: Liposomal encapsulation allows iron to bypass traditional iron uptake pathways, reducing the risk of oxidative stress and constipation.   ● Formulation Friendly: It remains stable in complex multi-nutrient blends where iron often triggers oxidation of other vitamins or minerals.   Empowering Our Partners’ Brands For procurement and R&D teams, LiposoMore™ offers more than just superior science. Joyful Nutritional provides comprehensive technical support, ensuring that the transition from raw material to finished product is seamless. Every batch of LiposoMore™ is produced under strict international quality standards, including GMP and ISO certifications, ensuring traceability and consistency.   As the "Premium Delivery Standard," LiposoMore™ enables brand owners to differentiate themselves in a crowded market by making "High Bioavailability" a verifiable label claim rather than just a marketing buzzword.  
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Latest company news about Highly Bioavailable Calcium Citrate Malate with A High Absorption Rate
2024-10-22

Highly Bioavailable Calcium Citrate Malate with A High Absorption Rate

  Highly Bioavailable Calcium Citrate Malate with A High Absorption Rate   1. What is Calcium Citrate Malate ?     Calcium Citrate Malate (CCM), also known as calcium citrate, is a neutral complex salt formed by malic acid, citric acid and calcium. The molecular formula and typical structure are shown in Figure 1.           2. Advantages of Calcium Citrate Malate compared to other calcium salts   1. Calcium Citate malate has the characteristics of high solubility, high absorption and utilization, safety and non-toxicity. Its water solubility is more than 100 times that of calcium carbonate and more than 10 times that of calcium citrate. Its aqueous solution is weakly acidic and its absorption and utilization rate is 37% higher than that of calcium carbonate.   2. Compared with calcium carbonate, calcium citrate malate as a calcium source does not consume gastric acid while supplementing calcium, and does not increase the risk of kidney stones.   3. Compared with other calcium nutritional enhancers, calcium citrate malate has the functions of supplementing calcium, enhancing bone density, regulating blood lipids, and enhancing oral health, reducing the risk of kidney stones, and not affecting the absorption of other trace elements.   4. Calcium citrate malate also has the physiological functions of malic acid such as anti-fatigue and heart protection. It can be used as a food additive and can also be directly made into calcium supplement health food, with broad development and application prospects.   3. High absorbability   The bioavailability of calcium refers to the proportion of calcium used by the body, which depends on many factors, including the number of "enhancing factors" and "hindering factors" and the acidity of the digestive environment. Studies have shown that malic acid and citric acid are the best absorbed substances for chelating minerals. Calcium is mainly absorbed in the duodenum, which is actively absorbed, and malic acid and citric acid are absorbed in the upper digestive tract. The biggest feature of calcium phosphate is that the human body has a high absorption rate of its calcium, and it also has high biological availability such as promoting bone formation and alleviating bone loss.       The high absorption of calcium hydroxyapatite has been confirmed by clinical experiments and animal experiments [2]. Miller et al. used single-label and double-label stable isotope technology to conduct clinical experiments on the calcium absorption rate of calcium carbonate and calcium hydroxyapatite. The calcium absorption rate of calcium hydroxyapatite reached (36.2±2.7)%, while the absorption rate of calcium carbonate was (26.4±2.2)%.   Wang Ling et al. [3] studied the effects of different calcium sources (calcium citrate malate group, solid calcium carbonate group, liquid calcium carbonate group, solid calcium carbonate plus vitamin D3 group and low calcium control group) on rat bone metabolism. Through the test results of six indicators including serum alkaline phosphatase, serum tartrate-resistant acid phosphatase, serum calcium, serum phosphorus, bone calcium and bone density, calcium citrate malate and solid calcium carbonate plus vitamin D3 had better effects on improving rat bone metabolism, indicating that organic acids and vitamin D3 can effectively promote calcium absorption.   Rzymski et al. [4] administered oral calcium pyruvate, calcium citrate malate, calcium carbonate, and placebo to 12 healthy postmenopausal women who had fasted before the intervention. They observed an increase in calcium levels within 180 minutes after ingestion, with calcium citrate malate providing the highest calcium levels (Figure 2).       Figure 2 Changes in serum calcium concentration after taking placebo or 1000 mg of different calcium sources   4. Little inhibitory effect on iron absorption   People mostly focus on supplementing a single dose of nutrients. When calcium and iron are taken at the same time, their interaction is often ignored. Hallerg et al.’s research suggests that oral calcium supplementation has a significant inhibitory effect on iron absorption, and there is a dose-response relationship. Other studies have shown that the effect of calcium on iron absorption is related to the time interval between the two intakes, and the inhibitory effect when ingested at the same time The strongest; oral calcium supplementation may affect the absorption of dietary iron, reduce circulating iron, and affect red blood cell production due to iron deficiency [5].   Wu Meiyin et al.[5] discussed the effects of three commonly used calcium agents, calcium citrate malate (CCM), calcium carbonate (CaCO3), and bone calcium (BC), combined with ferrous fumarate (FF) on calcium and iron absorption. and bioavailability of three calcium supplements.   Experimental results show that the CCM/FF combination can significantly increase the hemoglobin content (see Table 1) and serum iron content (see Table 2) in rats with iron deficiency anemia, indicating that CCM has a small inhibitory effect on iron absorption. In addition, the area under the calcitonin curve (AUC) of CCM is higher than that of CaCO3 and BC, which indirectly reflects that the absorption rate of CCM is higher than that of other calcium agents.         References: [1]. Jing Yiwen, Zhang Qiao, Yang Xiuyun, et al. Determination of 25 elemental impurities in calcium citrate malate[J]. Journal of Pharmaceutical Analysis, 2023, 43(7): 1229-1237. [2]. Wu Junlin, Wu Qingping, Zhang Jumei, Research progress on the physiological effects of calcium citrate malate. Food Science, 2010. 31(7): pp. 333-337. [3]. Wang Ling, et al., Effects of different calcium sources on bone metabolism in rats. Food and Fermentation Technology, 2017. 53(3): pp. 29-32. [4]. Rzymski, P., et al., The bioavailability of calcium in the form of pyruvate, carbonate, citrate–malate in healthy postmenopausal women. European Food Research and Technology, 2016. 242(1): p. 45-50. [5]. Wu Meiyin, Chen Shaojie, Yan Xiao, Effects of different calcium supplements on calcium and iron absorption in rats with iron deficiency anemia. Food Industry Science and Technology, 2015. 36(17): pp. 371-374.
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